Introduction – Energy is important for the physical and mental psychological transformation of a person. For this, the combination of new methods has been introduced that allows the delivery of drugs through the patches of micro-needle and drugs. This is known as the process of turning energy storage of white fat to energy burning of brown fat.
Research – A research have been conducted which shows the reduction in weight gain in a mice on a high fat diet and mass which should be more than 30 percent. The patches of new types of skin contains various micro-needles which helps in loading drug known as beta-3 adrenergic receptor agonist or the other drug that works as thyroid hormone known as T3 triiodothyronine. It is very thin than the human hair.
Process – When these patches are pressed into the skin, it will slowly diffused to the storing of energy white fat underneath of the layers of skin that helps in turning them into energy-burning brown fats. Brown fats are mostly found in babies that can help the baby to keep warm so that it can burn the energy. If the humans are growing older, the amount of brown fats have been reduced and replaced with visceral white fats.
Approach – This approach helps in addressing the obesity problem which is worldwide. It is without the surgical operations or oral medication that requires the large dosage with serious side effects. The embedding of micro-needles in the skin of the mice allows the surrounding of fats that started browning in five days. It helps in increasing the energy expenditure of mice that also leads to the reduction in body fat gain.
Creation – The amounts of drugs are used in creating the patches which is very less than the oral medication or injected dose. It enables the reduction in the costs of drug ingredients which slowly release the designs by minimizing its side effects. The obesity of a person results in the excessive accumulation of fat which is considered as the major health risk factor that works for various diseases. It includes stroke, heart disease and two-types of diabetes. A study has been made which made the estimation of around 1.9 billon adults in the world. It was overweighed in 2016 with 650 million obese people.
